Calculated reference model · not an experimental or batch-certified structure. All 17 atoms shown.
Model data & sources
- Heavy atoms only; hydrogens are omitted from the reference display.
- Source-defined stereochemistry is checked against the calculated coordinates; no energy-minimum, crystal or solution-structure claim is made.
- The source record leaves some stereochemistry unspecified. This calculated conformer does not establish a unique stereoisomer.
- Reference molecular species only; batch identity, purity, counterions and excipients are not certified.
- Formula
- C12H13ClN2O2
- Method
- RDKit ETKDGv3 / MMFF94s calculated reference conformer
RGPU-95 (p-CL-Phenylpiracetam)
RGPU-95 (p-Cl-Phenylpiracetam) Research Standard
RGPU-95 (p-Cl-Phenylpiracetam) is a synthetic racetam-class compound characterized by the addition of a chlorine atom to the phenylpiracetam scaffold. This structural modification is a focal point in pharmacological research, specifically investigated for how it alters the compound's stability, lipophilicity, and pharmacological potency in in vitro models. In laboratory settings, RGPU-95 is utilized as a high-potency tool for mapping signal transmission dynamics within nerve tissue and observing cellular responses to stressors in controlled experimental environments.
Physical & Handling Properties
| Property | Specification |
|---|---|
| Physical Appearance | Fine white powder |
| Solution Base | PEG400, DMSO |
Mechanism of Action & Research Context
The chemical modification of phenylpiracetam with a para-chlorine substituent is what distinguishes RGPU-95 from its parent scaffold.
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Ring Substitution: Chlorine is an electron-withdrawing substituent, so the para-chlorinated phenyl ring is deactivated toward electrophilic attack relative to the unsubstituted ring. What that means for the compound under experimental conditions is one of the things RGPU-95 is used to measure.
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Signaling Modulation: Research focuses on the compound's interaction with neurotransmitter pathways, particularly its ability to modulate signal velocity and transduction efficiency between neurons in cultured tissue.
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Cellular Resilience: Because the compound is utilized to study cells under "pressure," it acts as a valuable reference in experiments measuring how neural tissue maintains viability or signaling integrity when exposed to thermal or metabolic stress.
Research Applications
RGPU-95 is a specialized reference material for cognitive science and neuropharmacology.
Primary fields of in vitro laboratory investigation include:
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GABAergic Signaling: Investigating the modulation of GABA receptor activity in isolated nerve tissue models.
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Bioenergetic Stress Testing: Examining energy utilization in neural cells under low-temperature (cold stress) conditions.
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Permeability Studies: Investigating the kinetics of the compound's movement across cellular barriers and membrane systems.
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Signal Speed Dynamics: Quantifying changes in signal propagation speed between nerve cells in controlled culture environments.
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Comparative Neuropharmacology: Utilizing the chlorinated scaffold to compare binding and activity profiles against the parent phenylpiracetam molecule.
Storage & Handling Guidelines
Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Related Research Compounds
Research Use Disclaimer
Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only — NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.
