Skip to main content
KimeraCHEMS
Display
Out of stock
  • C
  • N
  • O

Calculated reference model · not an experimental or batch-certified structure. Backbone view: 65 of 125 atoms.

Model data & sources
  • Native hGH 176–191 sequence-derived reference with Cys7–Cys14 disulfide (native Cys182–Cys189), free peptide termini and no N-terminal tyrosine replacement.
  • PubChem CID 16131230 is not used: its graph does not match the independently declared peptide connectivity.
  • Reference molecular species only, not a supplied-batch identity certification.
  • The calculated homolog differs by its N-terminal Tyr hydroxyl. That atom is omitted; no new bond is invented.
  • This is a mapped calculated reference pose. No new force-field relaxation, observed native-fragment fold or minimum-energy claim is made.
  • Heavy atoms only; hydrogens are omitted from the display.
  • Reference molecular species only; batch composition is not certified.
Sequence
FLRIVQCRSVEGSCGF
Formula
C78H123N23O22S2
Method
Coordinate transfer from a calculated AOD-9604 homolog pose, revalidated against the independent native hGH 176–191 disulfide graph

Fragment 176-191

Peptides

Published formats

  • Standard Reference Vial

Supplementary product details from the published catalog, checked 2026-10-07. These reference details do not establish current availability.

Pricing

Pricing and order placement are reserved for reviewed research accounts. Log in or submit an account application to view current product pricing.

Log in to view priceApply for account

Want to be notified when this product is back in stock?

Technical Specifications

Batch COA Database ↗
CAS Registry Number66004-57-7
Molecular FormulaC₇₈H₁₂₅N₂₃O₂₃S₂
Molecular Weight1817.12
IUPAC Designation[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl] (4S)-5-[[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]oxy-2-oxoethyl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2R)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]-3-sulfanylidenepropanoyl]amino]pentanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoate
Physical FormRefer to product documentation
Storage RequirementsRefer to product documentation
Other NamesSomatotropin (176-191), DTXSID10216216, L-Phenylalanine, L-phenylalanyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamylglycyl-L-seryl-L-cysteinylglycyl-, cyclic (7-14)-disulfide

Identity fields from the published product record, checked 2026-10-07. Reference information is not a batch identity certificate.

Research Overview

Fragment 176-191 Research Standard

Fragment 176-191 (CAS 66004-57-7), indexed as somatotropin (176-191), is the unmodified C-terminal peptide of human growth hormone, supplied as a 5 mg lyophilized powder in a 3 mL vial. It is a cyclic disulfide-containing peptide fragment, and it is not the same material as AOD-9604 — a distinction the two are routinely sold without.

Mechanism of Action & Research Context

This fragment has no identified receptor and no established mechanism. Stating that plainly is more useful than assembling a mechanism section from claims made about a related molecule.

  • What distinguishes it from AOD-9604. AOD-9604 is the hGH C-terminal fragment residues 177–191 carrying an additional tyrosine at the N-terminus, and it holds a different CAS number. This product is the fragment without that modification. Any data generated on AOD-9604 — including its metabolite profile — describes that molecule, not this one.[1]

  • The region is analytically characterised, the unmodified fragment less so. Work on the C-terminal region has established detection methods and metabolite behaviour for the tyrosinated analogue. Independent characterisation of the unmodified 176-191 fragment is thinner, so comparative work between the two is a genuine gap rather than a settled question.[1]

  • Disulfide-containing. The fragment carries a cyclic disulfide, which matters for handling: reducing conditions will open it, and the reduced and oxidised forms are different analytes.

Research Applications

Primary fields of laboratory investigation include:

  • Comparative characterisation against AOD-9604, isolating the contribution of the N-terminal tyrosine.[1]

  • Analytical method development resolving the unmodified fragment from the tyrosinated analogue and their metabolites.[1]

  • Disulfide integrity and stability studies across oxidising and reducing conditions.

  • Peptide reference material for chromatographic and mass-spectrometric identification.

Analytical Documentation

Purity and identity vary by manufacturing lot. Kimera Chems does not publish a single fixed purity figure for this item; refer to the batch-specific Certificate of Analysis (COA) issued for the lot received, which reflects third-party analytical testing for that lot.

References

  1. Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D. Detection and in vitro metabolism of AOD9604. Drug Test Anal. 2015;7(1):31–38. doi:10.1002/dta.1715

Storage & Handling

Store at controlled room temperature, sealed and protected from light.

Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.

Related Research Compounds

Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only - NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.

Related products

Kimera Chems

Compounds That Survive Scrutiny

Research use only. Not for human or veterinary use.