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Humanin is a mitochondrial-derived peptide supplied as a lyophilized powder for laboratory research. Its sequence is Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala (24 residues). Researchers study it in cytoprotection and mitochondrial signalling models, where short peptides are used as tools for examining sequence-specific binding and protein interactions. Kimera Chems supplies this material for controlled laboratory studies only.
Chemical Composition & Purity
Humanin has the molecular formula C₁₁₉H₂₀₄N₃₄O₃₂S₂ and a molecular weight of 2687.24 g/mol. It appears as a white to off-white lyophilized powder. Purity for this lot is documented on its batch-specific Certificate of Analysis, available for batch KC-HMN-PUR1.
Research Applications
Humanin is used as a reference peptide in cell-free and in vitro systems. Its 24-residue sequence gives a defined three-dimensional shape, and the side chain charges determine how it behaves in binding studies.
- Receptor Binding: Measuring peptide-protein affinity in cell-free systems.
- Competitive Assays: Examining displacement of labeled ligands.
- Structural Studies: Analyzing folding patterns in solution.
- Stability Testing: Monitoring degradation under various conditions.
Storage & Handling Protocol
Store at controlled room temperature, sealed and protected from light.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Compliance & Usage Disclaimer
This product is for Research Use Only (RUO). It is not for human or animal consumption or clinical application. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.
