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Calculated reference model · not an experimental or batch-certified structure. All 12 atoms shown.

Model data & sources
  • The catalog lists the chloride salt. Only the 5-amino-1-methylquinolinium cation is drawn; the counterion is not shown or certified.
  • Heavy atoms only; hydrogens are omitted from the reference display.
  • Source-defined stereochemistry is checked against the calculated coordinates; no energy-minimum, crystal or solution-structure claim is made.
  • Reference molecular species only; batch identity, purity, counterions and excipients are not certified.
Formula
C10H11N2+
Method
RDKit ETKDGv3 / MMFF94s calculated reference conformer
In stock nowBrowse more certificates
Batch
KC-5AQ-05
Reports
2 on file
Everything shipping from this page today came off this batch. The code is printed on your label, and one certificate covers the whole batch.

5-Amino-1MQ

Aminos

Published formats

  • Dry-Fill Capsule 60ct/50mg/3g
  • Liquid Vial 20ml/50mg per ml/1g
  • Powder 5g
What is the difference between these?
Dry-Fill Capsule
Capsules filled with the weighed solid. The label gives the amount in each capsule and the number in the bottle.
Liquid Vial
The compound already in solution, in a sealed vial rather than a dropper bottle. The label gives the amount per millilitre, the volume and the total.
Powder
Raw material as a solid. Nothing added and nothing portioned; the stated weight is what is in the container.
Each label gives the amount per unit and the total, so compare the totals rather than the container size.

Supplementary product details from the published catalog, checked 2026-10-07. These reference details do not establish current availability.

Pricing

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Technical Specifications

Batch COA Database ↗
CAS Registry NumberNot assigned
Molecular FormulaC₁₀H₁₁ClN₂
Molecular Weight194.66
IUPAC Designation1-methylquinolin-1-ium-5-amine chloride
Physical FormOrange powder
Storage RequirementsRefer to product documentation
Solution VehicleDeionized Water, Benzyl Alcohol
Other Names5-Amino-1-methylquinolinium chloride; 5-Amino-1-methylquinolin-1-ium chloride; Quinolinium, 5-amino-1-methyl-, chloride (1:1); UNII-KK7LU6YQL5; KK7LU6YQL5
Capsule Concentration50mg x 60ct
Liquid Concentration and Solution50mg/ml Sterile Water, Benzyl Alcohol
Bulk Powder Quantity5g

Identity fields from the published product record, checked 2026-10-07. Reference information is not a batch identity certificate.

Research Overview

5-Amino-1MQ (Chloride) Research Standard

5-Amino-1MQ (5-Amino-1-methylquinolinium chloride) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). Unlike peptides, which are chains of amino acids, this compound is a cell-permeable small molecule that functions as an enzyme-pathway modulator. In laboratory research it is used as an inhibitor of NNMT-catalysed nicotinamide methylation in enzyme and cell assays.

Physical & Handling Properties

Property Specification
Physical Appearance Orange powder
Solution Base Deionized Water, Benzyl Alcohol

Mechanism of Action & Research Context

5-Amino-1MQ is studied as a selective inhibitor of a single enzyme, NNMT.

  • NNMT Inhibition: The compound acts as a substrate-targeting, selective inhibitor of NNMT. By inhibiting this enzyme, 5-Amino-1MQ prevents the methylation of nicotinamide into 1-methylnicotinamide (1-MNA).

  • NAD+ Pathway Modulation: Because NNMT consumes nicotinamide and methyl groups (SAM), its inhibition is hypothesized to preserve nicotinamide for the NAD+ salvage pathway.

  • NNMT Expression Mapping: It is used to relate NNMT expression and activity to nicotinamide and SAM turnover in cell models.

Research Applications

5-Amino-1MQ is a reagent for NNMT enzyme research.

Primary fields of in vitro and in vivo laboratory investigation include:

  • NNMT Enzyme Inhibition Studies: Quantifying the IC50 of the compound in various cell-free and cell-based enzyme assays.

  • NNMT Activity in Cell Lines: Measuring 1-MNA formation and SAM consumption in cultured cell lines (e.g., 3T3-L1) when NNMT is inhibited.

  • NAD+ Salvage Pathway Research: Measuring nicotinamide and NAD+ levels in cell assays when NNMT is inhibited.

  • Comparative Pharmacology: Benchmarking 5-Amino-1MQ against other NNMT inhibitors by IC50 and selectivity.

Storage & Handling Guidelines

Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.

Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.

Related Research Compounds

Further reading: 5-Amino-1MQ research overview

Research Use Disclaimer

Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only — NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.

Certificates of Analysis

Currently shipping from batch KC-5AQ-05.

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Research use only. Not for human or veterinary use.