Oxiracetam Research Standard
Oxiracetam (4-hydroxy-2-oxo-1-pyrrolidineacetamide) is a synthetic derivative of the piracetam family, characterized by the addition of a hydroxyl group to the pyrrolidone nucleus. This modification increases its potency compared to parent compounds, making it a staple in neuropharmacological research. Oxiracetam is primarily utilized as a specialized laboratory tool for investigating cognitive signaling pathways, specifically those related to cholinergic and glutamatergic neurotransmission, as well as cerebral energy metabolism in in vitro neural tissue models.
Technical Specifications
| Property | Specification |
|---|---|
| Product Name | Oxiracetam |
| Chemical Formula | C₆H₁₀N₂O₃ |
| Molecular Weight | 158.16 g/mol |
| Chemical Class | Racetam derivative |
| Physical Appearance | Fine crystalline white or off-white powder |
| Assay Purity | Refer to the batch-specific Certificate of Analysis (COA) supplied for the lot received |
Mechanism of Action & Research Context
Oxiracetam is studied for its ability to modulate key neurotransmitter systems and metabolic processes within the brain, particularly in contexts involving high-density neural information processing.
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Cholinergic and Glutamatergic Modulation: Research indicates that oxiracetam may influence the release of acetylcholine and the modulation of glutamate receptors, which are essential for synaptic plasticity and the formation of long-term potentiation (LTP).
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Metabolic Enhancement: The compound is evaluated for its capacity to optimize oxygen and glucose utilization pathways in neural tissues, potentially stabilizing ATP production in cell-based energy models.
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Signaling Efficacy: By targeting these pathways, oxiracetam is used to measure the rate at which neural networks adapt and reorganize, providing a quantitative model for studying memory and learning efficiency.
Research Applications
Oxiracetam is a versatile reference compound utilized for exploring cognitive pathways in controlled laboratory settings.
Primary fields of in vitro laboratory investigation include:
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Neurotransmitter Activity Mapping: Measuring glutamate-related signaling dynamics and cholinergic transmission in cultured hippocampal tissue.
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Cellular Bioenergetics: Testing the compound’s influence on mitochondrial glucose uptake and oxygen consumption during metabolic stress.
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Synaptic Plasticity: Observing the speed and fidelity of information storage/retrieval in controlled neuronal network models.
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Cognitive Pharmacology: Serving as a benchmark for comparing the potency and activity profile of newer synthetic racetam derivatives.
Storage & Handling Guidelines
Store at controlled room temperature. Keep tightly closed.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
References
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Valzelli L, et al. (1980) “Oxiracetam: a psychotropic drug with learning-enhancing properties.” Pharmacological Research Communications. 12(6): 579–583.
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Malykh AG, Sadaie MR. (2010) “Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.” Drugs. 70(3): 287–312.
Related Research Compounds
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this research material solely to qualified institutions and professional investigators for authorized laboratory research.
