RGPU-95 (p-Cl-Phenylpiracetam) Research Standard
RGPU-95 (p-Cl-Phenylpiracetam) is a synthetic racetam-class compound characterized by the addition of a chlorine atom to the phenylpiracetam scaffold. This structural modification is a focal point in pharmacological research, specifically investigated for how it alters the compound’s stability, lipophilicity, and pharmacological potency in in vitro models. In laboratory settings, RGPU-95 is utilized as a high-potency tool for mapping signal transmission dynamics within nerve tissue and observing cellular responses to stressors in controlled experimental environments.
Technical Specifications
| Property | Specification |
|---|---|
| Product Name | RGPU-95 (p-Cl-Phenylpiracetam) |
| Chemical Formula | C₁₂H₁₃ClN₂O₂ |
| Molecular Weight | ~238.67 g/mol |
| Chemical Class | Racetam derivative (Chlorinated) |
| Physical Appearance | Fine white powder |
| Assay Purity | Refer to the batch-specific Certificate of Analysis (COA) supplied for the lot received |
| Solution Base | PEG400, DMSO |
Mechanism of Action & Research Context
The chemical modification of phenylpiracetam with a para-chlorine substituent is what distinguishes RGPU-95 from its parent scaffold.
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Ring Substitution: Chlorine is an electron-withdrawing substituent, so the para-chlorinated phenyl ring is deactivated toward electrophilic attack relative to the unsubstituted ring. What that means for the compound under experimental conditions is one of the things RGPU-95 is used to measure.
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Signaling Modulation: Research focuses on the compound’s interaction with neurotransmitter pathways, particularly its ability to modulate signal velocity and transduction efficiency between neurons in cultured tissue.
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Cellular Resilience: Because the compound is utilized to study cells under “pressure,” it acts as a valuable reference in experiments measuring how neural tissue maintains viability or signaling integrity when exposed to thermal or metabolic stress.
Research Applications
RGPU-95 is a specialized reference material for cognitive science and neuropharmacology.
Primary fields of in vitro laboratory investigation include:
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GABAergic Signaling: Investigating the modulation of GABA receptor activity in isolated nerve tissue models.
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Bioenergetic Stress Testing: Examining energy utilization in neural cells under low-temperature (cold stress) conditions.
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Permeability Studies: Investigating the kinetics of the compound’s movement across cellular barriers and membrane systems.
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Signal Speed Dynamics: Quantifying changes in signal propagation speed between nerve cells in controlled culture environments.
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Comparative Neuropharmacology: Utilizing the chlorinated scaffold to compare binding and activity profiles against the parent phenylpiracetam molecule.
Storage & Handling Guidelines
Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Related Research Compounds
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this research material solely to qualified institutions and professional investigators for authorized laboratory research.
