Sunifiram (DM-235) Research Standard
Sunifiram (DM-235) is a highly potent synthetic compound belonging to the racetam class of chemicals. Distinguishable by its significantly increased potency compared to earlier molecules such as piracetam, Sunifiram is utilized in laboratory research as a powerful tool for investigating excitatory amino acid receptor signaling. In in vitro models, it serves as a reference material for probing the modulation of AMPA and NMDA receptors and observing the resulting changes in nerve cell activity, synaptic signaling, and cognitive-related neuroplasticity pathways.
Technical Specifications
| Property | Specification |
|---|---|
| Product Name | Sunifiram (DM-235) |
| Chemical Formula | C14H18N2O2 |
| Chemical Class | Racetam derivative |
| Physical Appearance | Fine white or off-white powder |
| Assay Purity | Refer to the batch-specific Certificate of Analysis (COA) supplied for the lot received |
| Solution Base | Phosphate Buffered Solution, EDTA |
Mechanism of Action & Research Context
Sunifiram is primarily investigated for its pharmacological impact on glutamatergic signaling systems in neural tissue.
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Receptor Modulation: The compound is characterized by its activity at both AMPA and NMDA receptors. It is hypothesized to function as a positive allosteric modulator, which enhances the signaling efficiency of these receptors in isolated cell preparations.
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Potency Profile: Due to its high binding affinity and potency relative to first-generation racetams, Sunifiram allows for the use of micro-gram scale dosing in experimental models, facilitating precise control over receptor activation concentrations.
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Signaling Pathways: Research utilizing Sunifiram focuses on its ability to potentiate synaptic transmission, making it a critical reagent for studying the mechanisms of long-term potentiation (LTP) and synaptic plasticity.
Research Applications
Sunifiram is a specialized reagent used to explore the dynamics of glutamatergic signaling and cognitive neurobiology.
Primary fields of in vitro laboratory investigation include:
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Memory & Plasticity Studies: Examining changes in hippocampal tissue model activity to understand the mechanisms of neuroplasticity.
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Synaptic Activity: Monitoring real-time signal propagation and movement between nerve cells in culture.
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Focus & Pathway Research: Observing pathway activity in attention-related research models.
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Receptor Signaling: Characterizing the dose-response relationship of AMPA/NMDA receptor activity in controlled nerve tissue environments.
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Comparative Racetam Analysis: Utilizing Sunifiram as a high-potency benchmark when comparing the efficacy of structurally diverse racetam-class compounds.
Storage & Handling Guidelines
Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Related Research Compounds
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this research material solely to qualified institutions and professional investigators for authorized laboratory research.
