KimeraCHEMS- C
- N
Calculated reference model · not an experimental or batch-certified structure. All 8 atoms shown.
Model data & sources
- The product is supplied as the hydrochloride salt. Only the amine parent molecule is drawn; the chloride counterion is not shown.
- Heavy atoms only; hydrogens are omitted from the reference display.
- Source-defined stereochemistry is checked against the calculated coordinates; no energy-minimum, crystal or solution-structure claim is made.
- The source record leaves some stereochemistry unspecified. This calculated conformer does not establish a unique stereoisomer.
- Reference molecular species only; batch identity, purity, counterions and excipients are not certified.
- Formula
- C7H17N
- Method
- RDKit ETKDGv3 / MMFF94s calculated reference conformer
- Batch
- KC-DM4-01
1,4-Dimethylamylamine
Research CompoundsPublished formats
- Liquid Dropper 30mL/100mg Per mL/3g
- Powder 5g
What is the difference between these?
- Liquid Dropper
- The compound already in solution, in a dropper bottle. The label gives the amount per millilitre, the bottle volume and the total.
- Powder
- Raw material as a solid. Nothing added and nothing portioned; the stated weight is what is in the container.
Supplementary product details from the published catalog, checked 2026-10-07. These reference details do not establish current availability.
Pricing
Pricing and order placement are reserved for reviewed research accounts. Log in or submit an account application to view current product pricing.
Technical Specifications
Batch COA Database ↗Identity fields from the published product record, checked 2026-10-07. Reference information is not a batch identity certificate.
Research Overview
1,4-Dimethylamylamine Research Standard
1,4-Dimethylamylamine (5-methylhexan-2-amine) is a synthetic aliphatic amine and a structural isomer of Methylhexaneamine. As a sympathomimetic amine, it serves as a specialized reagent in adrenergic research, primarily employed to investigate how the positioning of alkyl substitutions on an aliphatic amine chain influences receptor binding affinity and sympathomimetic potency. In laboratory research, it acts as a tool for probing the structural requirements for norepinephrine release and adrenergic receptor modulation within neuronal and physiological models.
Physical & Handling Properties
| Property | Specification |
|---|---|
| Physical Appearance | White to pale yellow powder |
| Solubility | Soluble in water and common organic solvents |
| Solution Base | Deionized Water, Ethanol |
Mechanism of Action & Research Context
Research into 1,4-Dimethylamylamine focuses on its properties as an indirect sympathomimetic agent, providing a comparative model to its 1,3-isomer.
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Adrenergic Modulation: Like other aliphatic amines in this class, 1,4-Dimethylamylamine functions by facilitating the release of norepinephrine from presynaptic storage vesicles. This leads to an increased concentration of catecholamines within the synaptic cleft, stimulating postsynaptic adrenergic receptors.
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Structural Isomerism & SAR: The primary research utility of 1,4-Dimethylamylamine lies in Structure-Activity Relationship (SAR) studies. By comparing 1,4-Dimethylamylamine with Methylhexaneamine, investigators can elucidate how the displacement of the methyl group along the aliphatic backbone alters the molecule's interaction with the norepinephrine transporter (NET) and its subsequent effect on neurotransmitter release.
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Receptor Pharmacology: Investigations utilize this compound to determine whether variations in the aliphatic chain significantly impact the potency of the resultant adrenergic response, helping to map the steric requirements of the transporter binding site.
Research Applications
1,4-Dimethylamylamine is a specialized reagent essential for comparative pharmacological research and adrenergic signaling studies.
Primary fields of in vitro and laboratory investigation include:
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Structure-Activity Relationship (SAR) Panels: Benchmarking 1,4-Dimethylamylamine against other aliphatic isomers (e.g., Methylhexaneamine) to define the influence of molecular geometry on sympathomimetic activity.
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Adrenergic Signaling Pathways: Analyzing the release kinetics of catecholamines in neuronal cell models to compare efficacy across different amine scaffolds.
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Transporter Interaction Studies: Elucidating how different aliphatic amine structures interact with catecholamine reuptake transporters.
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Receptor Potency Analysis: Comparing the signaling output of 1,4-Dimethylamylamine in adrenergic receptor-transfected cell lines to assess subtype specificity and affinity.
Storage & Handling Guidelines
Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Related Research Compounds
Research Use Disclaimer
Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only — NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.
Currently shipping from batch KC-DM4-01.
Compounds That Survive Scrutiny
Research use only. Not for human or veterinary use.