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Calculated reference model · not an experimental or batch-certified structure. All 21 atoms shown.

Model data & sources
  • Heavy atoms only; hydrogens are omitted from the reference display.
  • Source-defined stereochemistry is checked against the calculated coordinates; no energy-minimum, crystal or solution-structure claim is made.
  • Reference molecular species only; batch identity, purity, counterions and excipients are not certified.
Formula
C19H24O2
Method
RDKit ETKDGv3 / MMFF94s calculated reference conformer

Arimistane

Research Compounds

Published formats

  • Dry-Fill Capsule 60ct/25mg/1.5g
  • Powder 5g
What is the difference between these?
Dry-Fill Capsule
Capsules filled with the weighed solid. The label gives the amount in each capsule and the number in the bottle.
Powder
Raw material as a solid. Nothing added and nothing portioned; the stated weight is what is in the container.
Each label gives the amount per unit and the total, so compare the totals rather than the container size.

Supplementary product details from the published catalog, checked 2026-10-07. These reference details do not establish current availability.

Pricing

Pricing and order placement are reserved for reviewed research accounts. Log in or submit an account application to view current product pricing.

Technical Specifications

Batch COA Database ↗
CAS Registry Number1420-49-1
Molecular FormulaC19H24O2
Molecular Weight284.39
IUPAC Designation(8R,9S,10R,13S,14S)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-7,17-dione
Physical FormRefer to product documentation
Storage RequirementsRefer to product documentation
Other NamesAndrosta-3,5-diene-7,17-dione, Androst-3,5-diene-7,17-dione, 3,5-Androstadiene-7,17-dione, MSK011040-100A, MSK011040-1000A
Capsule Concentration25mg x 60ct
Bulk Powder Quantity5g

Identity fields from the published product record, checked 2026-10-07. Reference information is not a batch identity certificate.

Research Overview

Arimistane

Arimistane, chemically identified as Androsta-3,5-diene-7,17-dione, is a synthetic, non-steroidal aromatase inhibitor. Structurally derived from the androstane family, it functions as an irreversible “suicide” inhibitor of the aromatase enzyme. It is utilized in laboratory settings for experimental endocrine research, focusing on the mapping of androgen-estrogen balance and estrogen pathway suppression.

Research Applications & Mechanism of Interest

Arimistane is primarily studied for its ability to bind irreversibly to the aromatase (CYP19A1) enzyme. By acting as a suicide inhibitor, the compound prevents the conversion of androgens to estrogens in controlled laboratory systems, and enzyme activity does not recover until new aromatase enzymes are synthesized.

Key fields of investigative research include:

  • Enzyme Kinetics: Utilizing the compound in aromatase inhibition assays to determine the duration of action and mechanistic suppression of estrogen synthesis.

  • Endocrine Signaling: Serving as a comparator compound in studies regarding estrogen-pathway suppression and the broader endocrine signaling environment.

  • Structure-Activity Relationship (SAR): Employing the molecule in comparative research to distinguish between steroidal and non-steroidal aromatase inhibitor behaviors.

  • Pathway Validation: Providing a tool for the structural validation of androgen-estrogen balance models.

Storage & Handling Guidelines

Store at controlled room temperature. Keep tightly closed.

Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.

Related Research Compounds

Frequently Asked Research Questions

Is Arimistane classified as an anabolic steroid?

While Arimistane is a synthetic androstane derivative, it is not classified as an anabolic steroid in research literature; it is studied specifically for its aromatase inhibition properties.

What is the significance of Arimistane’s “suicide inhibitor” mechanism?

In research models, because it binds irreversibly to the aromatase enzyme, the inhibition persists until the system synthesizes new aromatase enzymes, providing a reliable marker for duration-of-action studies.

Is pharmacokinetic data available for Arimistane?

Bioavailability and pharmacokinetic data are restricted to experimental laboratory models; there is no approved human pharmacokinetic data available.

Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only — NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.

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Compounds That Survive Scrutiny

Research use only. Not for human or veterinary use.