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Calculated reference model · not an experimental or batch-certified structure. All 21 atoms shown.

Model data & sources
  • The product is supplied as the hydrochloride salt. Only the tropisetron parent molecule is drawn; the chloride counterion is not shown.
  • Heavy atoms only; hydrogens are omitted from the reference display.
  • Source-defined stereochemistry is checked against the calculated coordinates; no energy-minimum, crystal or solution-structure claim is made.
  • Reference molecular species only; batch identity, purity, counterions and excipients are not certified.
Formula
C17H20N2O2
Method
RDKit ETKDGv3 / MMFF94s calculated reference conformer
In stock nowBrowse more certificates
Batch
KC-TPS-01
Reports
3 on file
Everything shipping from this page today came off this batch. The code is printed on your label, and one certificate covers the whole batch.

Tropisetron

Nootropics

Published formats

  • Powder 1g
  • Tablets 30ct/20mg/600mg
  • Liquid Dropper 30ml/20mg Per ml/600mg
What is the difference between these?
Powder
Raw material as a solid. Nothing added and nothing portioned; the stated weight is what is in the container.
Tablets
Pressed tablets. The label gives the amount in each tablet and the number in the bottle.
Liquid Dropper
The compound already in solution, in a dropper bottle. The label gives the amount per millilitre, the bottle volume and the total.
Each label gives the amount per unit and the total, so compare the totals rather than the container size.

Supplementary product details from the published catalog, checked 2026-10-07. These reference details do not establish current availability.

Pricing

Pricing and order placement are reserved for reviewed research accounts. Log in or submit an account application to view current product pricing.

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Technical Specifications

Batch COA Database ↗
CAS Registry Number105826-92-4
Molecular FormulaC₁₇H₂₀N₂O₂•HCl
Molecular Weight320.8
IUPAC Designation1H-indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride
Physical FormOff Pink Crystalline
Storage RequirementsRefer to product documentation
Solution VehicleAcetate Buffered Deionized Water
Other NamesTropisetron, Tropisetron HCl, Tropisetron Hydrochloride, ICS 205-930, SDZ-ICS 930
Liquid Concentration and Solution20mg Per mL Acetate Buffered Deionized Water
Bulk Powder Quantity1g
Tablet Concentration20mg x 30ct

Identity fields from the published product record, checked 2026-10-07. Reference information is not a batch identity certificate.

Research Overview

Tropisetron HCL (5-HT3 Receptor Antagonist) Research Standard

Tropisetron HCL is a synthetic indole derivative featuring a tropane ring structure, widely utilized in laboratory research as a potent and selective 5-HT3 receptor antagonist. By blocking the 5-HT3 receptor, the compound serves as a vital chemical probe for studying serotonergic signaling pathways. In controlled in vitro models, researchers leverage its structural profile—featuring both an indole ring system and a tropane nitrogen—to explore receptor-binding kinetics, competition dynamics, and the physiological consequences of inhibiting 5-HT3 receptor activation.

Physical & Handling Properties

Property Specification
Physical Appearance Off Pink Crystalline
Solution Base Acetate Buffered Deionized Water

Mechanism of Action & Research Context

Tropisetron HCL is primarily studied for its pharmacological activity as a serotonin (5-HT3) receptor antagonist.

  • 5-HT3 Antagonism: The compound acts by competitively binding to the 5-HT3 receptor, thereby inhibiting the activation of this ligand-gated ion channel. Research focuses on the impact of this inhibition on ion flux and downstream serotonergic signaling.

  • Structural Interaction: Its indole moiety participates in π-π stacking interactions, while the tropane nitrogen provides ionic stabilization, allowing the molecule to lock into the receptor’s binding site effectively.

  • Signaling Pathways: Scientists use Tropisetron HCL to investigate 5-HT3 receptor-mediated pathways in cell-free and cell-based assay systems, contributing to a broader understanding of serotonergic modulation in neurological and physiological research.

Research Applications

Tropisetron HCL is a specialized reagent essential for molecular signaling and neuropharmacological research.

Primary fields of in vitro laboratory investigation include:

  • Receptor-Binding Dynamics: Measuring the affinity and occupancy of the compound at 5-HT3 receptor sites.

  • Serotonergic Signaling: Evaluating the physiological effects of inhibiting 5-HT3 receptor-mediated neurotransmission in isolated neural preparations.

  • Competition Assays: Investigating how the compound competes with serotonin and other agonists for 5-HT3 receptor sites.

  • Structure-Activity Analysis: Mapping the specific molecular requirements of the indole/tropane scaffold for antagonist efficacy.

Storage & Handling Guidelines

Store at controlled room temperature. Keep tightly closed. Liquid formats: do not refrigerate or freeze. Cold storage may cause the solution to cloud or precipitate. If this occurs, return to room temperature and mix until clear.

Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.

Related Research Compounds

Research Use Disclaimer

Research Use Only Disclaimer: This product is labeled and sold "For Research Use Only — NOT FOR HUMAN CONSUMPTION." It is not a drug, dietary supplement, food, cosmetic, or medical device, and it is not approved by the FDA or any other regulator for human or veterinary use. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.

Certificates of Analysis

Currently shipping from batch KC-TPS-01.

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Compounds That Survive Scrutiny

Research use only. Not for human or veterinary use.