Calculated reference model · not an experimental or batch-certified structure. Backbone view: 97 of 187 atoms.
Model data & sources
- Heavy atoms only; hydrogens are omitted from the reference display.
- Source-defined atom stereochemistry is checked against the calculated coordinates; no energy-minimum or observed-fold claim is made.
- Reference molecular species only; batch counterions, excipients and material composition are not certified.
- Force-field relaxation reached its iteration limit. This is a geometry-checked reference, not a proven equilibrated or minimum-energy structure.
- Sequence
- MAPRGFSCLLLLTSEIDLPVKRRA
- Formula
- C119H204N34O32S2
- Method
- Source-identical PeptideBuilder idealized backbone / MMFF94s calculated reference conformer
Humanin
Humanin is a mitochondrial-derived peptide supplied as a lyophilized powder for laboratory research. Its sequence is Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala (24 residues). Researchers study it in cytoprotection and mitochondrial signalling models, where short peptides are used as tools for examining sequence-specific binding and protein interactions. Kimera Chems supplies this material for controlled laboratory studies only.
Chemical Composition & Purity
Humanin has the molecular formula C₁₁₉H₂₀₄N₃₄O₃₂S₂ and a molecular weight of 2687.24 g/mol. It appears as a white to off-white lyophilized powder. Purity for this lot is documented on its batch-specific Certificate of Analysis, available for batch KC-HMN-PUR1.
Research Applications
Humanin is used as a reference peptide in cell-free and in vitro systems. Its 24-residue sequence gives a defined three-dimensional shape, and the side chain charges determine how it behaves in binding studies.
- Receptor Binding: Measuring peptide-protein affinity in cell-free systems.
- Competitive Assays: Examining displacement of labeled ligands.
- Structural Studies: Analyzing folding patterns in solution.
- Stability Testing: Monitoring degradation under various conditions.
Storage & Handling Protocol
Store at controlled room temperature, sealed and protected from light.
Storage guidance is a house recommendation. Analytical documentation is per-lot release testing.
Compliance & Usage Disclaimer
This product is for Research Use Only (RUO). It is not for human or animal consumption or clinical application. It is supplied to approved account holders as a research chemical for laboratory use and must be handled in accordance with applicable law.
